hrp0084p3-872 | Fat | ESPE2015

Evaluation of Alternatives to OGTT to Assess Glucose Intolerance and Diabetes in an Obese Paediatric Population

Elowe-Gruau Eglantine , Bouthors Therese , Vadnai Gael , Buzduga Mihaela , Laufer Daniel , Decarli Manuela , Borloz Sylvie , Stoppa-Vaucher Sophie , Phan-Hug Franziska , Hauschild Michael , Pitteloud Nelly

Background: Screening for glucose intolerance (GI) or type 2 diabetes (T2D) is recommended for obese children over 10 years of age (or onset of puberty) in the presence of ≧2 of the following risk factors: family history of T2D in a first- or second-degree relative, high risk ethnicity, signs of insulin resistance (IR) or associated conditions, or maternal gestational diabetes. The diagnostic importance of HbA1C levels is still controversial in children and adolescents....

hrp0086p2-p517 | Fat Metabolism and Obesity P2 | ESPE2016

Polycystic Ovarian Syndrome in a Population of Obese Adolescents

Elowe-Gruau Eglantine , Ameti Adelina , Gonzalez Elena , Vial Yvan , Renteria Saira-Christine , Bouthors Therese , Borloz Sylvie , Puder Jardena , Stoppa-Vaucher Sophie , Phan-Hug Franziska , Dwyer Andrew , Hauschild Michael , Pitteloud Nelly

Background: Polycystic ovarian syndrome (PCOS) is the most common endocrine disease among women of reproductive age with a prevalence of about 8% according to the Androgen Excess Society (AES) criteria. The pathophysiology of PCOS is not well understood and it is associated with a high prevalence of metabolic disorders. During puberty, irregular menses and acne are common, thus making the diagnosis of PCOS in adolescence challenging.Objective and hypothe...